A Multidisciplinary Approach Evaluating Soybean Meal-Induced Enteritis in Rainbow Trout Oncorhynchus mykiss

This study evaluated a diverse range of markers feeding stress to obtain more precise assessment the welfare rainbow trout in relation inadequate husbandry conditions. A model based on dietary soybean meal was employed identify suitable minimally invasive “classical” markers, together with molecular signatures. In 56-day experiment, were fed diets containing different levels meal. The impact these assessed by water quality analyses, clinical health observations, classic growth and performance parameters, gut histopathology, blood-parameter measurements multigene-expression profiling RNA from whole blood. Soybean meal-induced enteritis manifested phenotypically an inflammatory reaction posterior section intestine diarrhoea some trout. These changes associated decreased supranuclear vacuolation. haematocrit values plasma cortisol circulating lymphocytes blood increased that had consumed high amounts SBM. Notably, depended significantly bodyweight individual transcript certain genes (e.g., MAP3K1, LYG, NOD1, STAT1 HSP90AB) emerged as potentially useful indicators providing valuable information about nutrition. expression-profiling findings provide basis for improved, monitoring regimens farming may stimulate development practical detection devices innovative aquaculture operations.